Organ Transplantation Research Today is a free monthly online journal that collates and summarizes the latest research about Organ Transplantation, including details on risks, prognosis, procedure, surgery.

Use of recombinant factor VII to control bleeding in a patient supported by right ventricular assist device after heart transplantation.

Kogan A, Berman M, Kassif Y, Raanani E, Stamler A, Ben Gal T, Stein M, Erez E, Vidne BA, Sahar G

Department of Cardiothoracic Surgery, Rabin Medical Center, Beilinson Campus, Petach Tikva 49100, Israel. akogan@clalit.org.il

A 48-year-old man undergoing orthotopic heart transplantation for ischemic cardiomyopathy developed severe right heart failure. Severe intractable bleeding complicated implantation of a right ventricular assist device. Treatment with 9.6 mg of recombinant activated factor VII stopped the bleeding, and the patient could be transferred to the intensive care unit. This is the first reported case of the successful use of recombinant activated factor VII to control bleeding with subsequent right ventricular assist device function.

Published 1 March 2005 in J Heart Lung Transplant, 24(3): 347-9.
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