Organ Transplantation Research Today is a free monthly online journal that collates and summarizes the latest research about Organ Transplantation, including details on risks, prognosis, procedure, surgery.

Schistosomal colitis without granuloma formation in a kidney transplant recipient.

Mudawi HM, Elhassan EA, Baraka OZ, El Hassan AM

Department of Internal Medicine, Faculty of Medicine, University of Khartoum, PO Box 2245, Khartoum, Sudan. hmudawi@hotmail.com

BACKGROUND: A 40-year-old male from the White Nile region in Sudan, who had received a kidney transplant 6 years previously, presented with fever, lower abdominal pain and diarrhea stained with blood of 5 months duration. He was on immunosuppressive maintenance therapy, consisting of ciclosporin 75 mg twice daily, prednisolone 10 mg once daily, and azathioprine 75 mg once daily. INVESTIGATIONS: Laboratory investigations, liver function tests, renal function tests, stool microscopy, stool culture, abdominal ultrasound, and colonoscopy. DIAGNOSIS: Severe, left-sided colitis due to Schistosoma mansoni infection, without granuloma formation. MANAGEMENT: Oral antischistosomal therapy with praziquantel at a dose of 40 mg/kg body weight.

Published 28 November 2006 in Nat Clin Pract Gastroenterol Hepatol, 3(12): 700-4.
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