Organ Transplantation Research - Risks, Prognosis, Procedure, Surgery

Organ Transplantation Research Today is a free monthly online journal that collates and summarizes the latest research about Organ Transplantation, including details on risks, prognosis, procedure, surgery.


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Factors influencing secondary alveolar bone grafting in cleft lip and palate patients: prospective analysis using CT image analyzer.

Ozawa T, Omura S, Fukuyama E, Matsui Y, Torikai K, Fujita K

Department of Oral and Maxillofacial Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan. ozawa@urahp.yokohama-cu.ac.jp

OBJECTIVE: To examine the effect of migration of the germ of the lateral incisor into the bone for eruption factors on bone bridge resorption. METHODS: Twenty-five subjects who underwent secondary alveolar bone graft were enrolled. The volume of the alveolar bone grafts immediately after the operation (V1), bone bridge formation 6 months postoperatively (V2), and tooth (teeth) migration into the bone bridge (Vt) were measured using a computed tomography (CT) image analyzer. Based upon these measurements, the following points were examined: (1) the correlation between the tooth-occupied ratio (Rt = Vt/V2 x 100) and the ratio of bone bridge resorption (Rv = (V1 - V2)/ V1 x 100); and (2) comparison of the tooth-occupied ratio (Rt) and the ratio of bone bridge resorption (Rv) between the groups with and without the germ of the lateral incisor. RESULTS: A significant negative correlation was found between Rv and Rt (p < .001). Comparison of Rv and Rt between the groups with and without a germ of the lateral incisor revealed that both indices were significantly higher in the former group than the latter one (p < .05). CONCLUSION: In cleft lip and palate patients with a germ of the lateral incisor, it is beneficial to carry out secondary bone grafting to the alveolar cleft at the age of 5 to 7 years, preceding eruption of the canine, in order to form a good bone bridge that will facilitate eruption of the lateral incisor and subsequent normal dentition and occlusion.

Published 4 May 2007 in Cleft Palate Craniofac J, 44(3): 286-91.
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